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Search Results to Theodore W Randolph

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Randolph, Theodore

One or more keywords matched the following items that are connected to Randolph, Theodore

Item Type	Name
Academic Article	Effects of phase separating systems on lyophilized hemoglobin.
Academic Article	Manipulation of lyophilization-induced phase separation: implications for pharmaceutical proteins.
Academic Article	Effects of Tween 80 and sucrose on acute short-term stability and long-term storage at -20 degrees C of a recombinant hemoglobin.
Academic Article	Aggregation of recombinant human interferon gamma: kinetics and structural transitions.
Academic Article	Conformational stability of lyophilized PEGylated proteins in a phase-separating system.
Academic Article	Tween protects recombinant human growth hormone against agitation-induced damage via hydrophobic interactions.
Academic Article	Effect of Tween 20 on freeze-thawing- and agitation-induced aggregation of recombinant human factor XIII.
Academic Article	Investigation of protein-surfactant interactions by analytical ultracentrifugation and electron paramagnetic resonance: the use of recombinant human tissue factor as an example.
Academic Article	High pressure fosters protein refolding from aggregates at high concentrations.
Academic Article	Molten globule intermediate of recombinant human growth hormone: stabilization with surfactants.
Academic Article	Preferential exclusion of sucrose from recombinant interleukin-1 receptor antagonist: role in restricted conformational mobility and compaction of native state.
Academic Article	Aggregation of granulocyte colony stimulating factor under physiological conditions: characterization and thermodynamic inhibition.
Academic Article	Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony-stimulating factor.
Academic Article	A transient expansion of the native state precedes aggregation of recombinant human interferon-gamma.
Academic Article	Mechanism for benzyl alcohol-induced aggregation of recombinant human interleukin-1 receptor antagonist in aqueous solution.
Academic Article	Heterogeneous nucleation-controlled particulate formation of recombinant human platelet-activating factor acetylhydrolase in pharmaceutical formulation.
Academic Article	Temperature dependence of benzyl alcohol- and 8-anilinonaphthalene-1-sulfonate-induced aggregation of recombinant human interleukin-1 receptor antagonist.
Academic Article	Effects of solutes on solubilization and refolding of proteins from inclusion bodies with high hydrostatic pressure.
Academic Article	Specific volume and adiabatic compressibility measurements of native and aggregated recombinant human interleukin-1 receptor antagonist: density differences enable pressure-modulated refolding.
Academic Article	Oxidation of methionine residues in recombinant human interleukin-1 receptor antagonist: implications of conformational stability on protein oxidation kinetics.
Academic Article	Stability of a trivalent recombinant protein vaccine formulation against botulinum neurotoxin during storage in aqueous solution.
Academic Article	Overlooking subvisible particles in therapeutic protein products: gaps that may compromise product quality.
Academic Article	Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products.
Academic Article	Crystallization of recombinant human growth hormone at elevated pressures: pressure effects on PEG-induced volume exclusion interactions.
Academic Article	Immunogenicity of recombinant human interferon beta interacting with particles of glass, metal, and polystyrene.
Academic Article	The effects of Tween 20 and sucrose on the stability of anti-L-selectin during lyophilization and reconstitution.
Academic Article	Optimizing storage stability of lyophilized recombinant human interleukin-11 with disaccharide/hydroxyethyl starch mixtures.
Academic Article	Effects of benzyl alcohol on aggregation of recombinant human interleukin-1-receptor antagonist in reconstituted lyophilized formulations.
Academic Article	High-pressure studies of aggregation of recombinant human interleukin-1 receptor antagonist: thermodynamics, kinetics, and application to accelerated formulation studies.
Academic Article	Effects of additives on the stability of recombinant human factor XIII during freeze-drying and storage in the dried solid.
Academic Article	Protein formulation and lyophilization cycle design: prevention of damage due to freeze-concentration induced phase separation.
Academic Article	Population balance modeling of aggregation kinetics of recombinant human interleukin-1 receptor antagonist.
Academic Article	Surface adsorption of recombinant human interferon-gamma in lyophilized and spray-lyophilized formulations.
Academic Article	Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-gamma.
Academic Article	Effects of pH, temperature, and sucrose on benzyl alcohol-induced aggregation of recombinant human granulocyte colony stimulating factor.
Academic Article	Effect of pH on stability of recombinant botulinum serotype A vaccine in aqueous solution and during storage of freeze-dried formulations.
Academic Article	Quantitation of aggregate levels in a recombinant humanized monoclonal antibody formulation by size-exclusion chromatography, asymmetrical flow field flow fractionation, and sedimentation velocity.
Academic Article	High concentration formulations of recombinant human interleukin-1 receptor antagonist: II. Aggregation kinetics.
Academic Article	High concentration formulations of recombinant human interleukin-1 receptor antagonist: I. Physical characterization.
Academic Article	Refolding of proteins from inclusion bodies is favored by a diminished hydrophobic effect at elevated pressures.
Academic Article	Immunogenicity of aggregates of recombinant human growth hormone in mouse models.
Academic Article	Recombinant murine growth hormone from E. coli inclusion bodies: expression, high-pressure solubilization and refolding, and characterization of activity and structure.
Academic Article	Glass particles as an adjuvant: a model for adverse immunogenicity of therapeutic proteins.
Concept	Recombinant Proteins
Academic Article	Stabilization of a recombinant ricin toxin A subunit vaccine through lyophilization.
Academic Article	Protein quantity on the air-solid interface determines degradation rates of human growth hormone in lyophilized samples.
Academic Article	Recombinant murine growth hormone particles are more immunogenic with intravenous than subcutaneous administration.
Academic Article	Effect of benzyl alcohol on recombinant human interleukin-1 receptor antagonist structure and hydrogen-deuterium exchange.
Academic Article	Do not drop: mechanical shock in vials causes cavitation, protein aggregation, and particle formation.
Academic Article	The Role of Protein Excipient in Driving Antibody Responses to Erythropoietin.
Academic Article	Protein-protein interactions controlling interfacial aggregation of rhIL-1ra are not described by simple colloid models.
Academic Article	Nanobubbles in Reconstituted Lyophilized Formulations: Interaction With Proteins and Mechanism of Formation.

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Recombinant Proteins